Kathleen M. Vogel, Students from PLCY 306 // #Crispr goes global: A snapshot of rules, policies, and attitudes | Bulletin of the Atomic Scientists

Crispr, compared to traditional methods of genetic engineering, enables more precise and efficient genetic modifications. The modifications are achieved by using small strands of RNA to guide a Crispr-associated protein, such as a Cas protein, to a specific location on an organism’s DNA. The Cas protein then cuts the DNA at an exact location, allowing an altered gene to insert itself at that location—or allowing modification of the nucleotide sequence at that site. All these attributes have sparked great excitement, and provoked many concerns, regarding the economic, social, biosafety, bioethical, and biosecurity implications of Crispr-related work. In the United States, the US National Academies of Science have hosted a variety of domestic and international meetings and issued reports on the potential promises and pitfalls of gene editing. Gene editing was included in the Worldwide Threat Assessment reports submitted to Congress by the Office of the Director of National Intelligence in 2016 and 2017.

Source: Crispr goes global: A snapshot of rules, policies, and attitudes | Bulletin of the Atomic Scientists

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